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This week's highest-impact publications across 29 specialties, curated by AI

Last updated: Jul 13, 2026

Rheumatology5 articles

Impact 2

FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review).

Published: 2026-09-01

International journal of molecular medicine

Medical Digest Indexed: 2026-07-12

This review discusses the role of Fibroblast growth factor receptor 1 (FGFR1) in rheumatoid arthritis (RA), highlighting its upregulation in inflamed joints and its involvement in bone loss and cartilage degradation. The findings suggest that targeting FGFR1 could significantly reduce bone loss a...

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Impact 2

Decoding the lipid etiology of atherogenic index of plasma and gout: establishing the causal role of triglycerides through NHANES, Mendelian randomization, and network pharmacology.

Published: 2026-07-13

Cardiovascular diabetology. Endocrinology reports

Medical Digest Indexed: 2026-07-14

This study investigates the causal relationships between the atherogenic index of plasma (AIP) and gout, focusing on its components triglycerides (TG) and HDL-C. The findings indicate that AIP is positively associated with gout prevalence, primarily mediated by HDL-C. TG is shown to have a signif...

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Impact 2

Injectable, Reactive Oxygen Species-Responsive Collagen Hydrogel for Peptide-Directed and On-Demand Nanotherapy of Osteoarthritis.

Published: 2026-07-13

ACS biomaterials science & engineering

Medical Digest Indexed: 2026-07-14

This study presents a novel peptide-modified collagen hydrogel that responds to reactive oxygen species (ROS) for targeted cartilage regeneration in osteoarthritis. The hydrogel enhances mechanical integrity and stability while promoting chondrogenesis and macrophage polarization in vitro. In viv...

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Impact 3

Comparative Effectiveness of a Nurse-Led Care Model vs Usual Care in Rheumatoid Arthritis: A Longitudinal Cohort Study of Clinical Outcomes and Patient Adherence.

Published: 2026-07-12

Medical science monitor : international medical journal of experimental and clinical research

Medical Digest Indexed: 2026-07-13

This study investigates the impact of a specialized nurse-led care (NC) model on clinical remission rates in rheumatoid arthritis (RA) patients over 12 months. A total of 415 patients were analyzed, revealing that the NC group achieved a remission rate of 41.7%, significantly higher than the usua...

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Impact 2

Gastrointestinal perforation due to lupus enteritis in early-stage systemic lupus erythematosus.

Published: 2026-07-12

Modern rheumatology case reports

Medical Digest Indexed: 2026-07-13

This case report discusses a 31-year-old man with systemic lupus erythematosus who developed lupus enteritis leading to colonic perforation. Despite initial treatments, he experienced worsening abdominal pain and was found to have extensive necrosis and perforation of the descending colon. Emerge...

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