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Tendencias en Investigación Médica

Las publicaciones de mayor impacto de la semana en 29 especialidades, seleccionadas por IA

Última actualización: 13 jul 2026

Hematología5 artículos

Impacto 3

Homoharringtonine in combination with Tanshinone IIA suppresses the progression of lymphoma cells by downregulating the Akt/MMP signaling pathway.

Publicado: 2026-08-01

Cytotechnology

Medical Digest Indexado: 2026-07-13

This study investigates the effects of homoharringtonine (HHT) and tanshinone IIA (Tan IIA) on lymphoma cells, demonstrating that their combined treatment significantly inhibits cell viability and proliferation, induces apoptosis, and lowers VEGF levels. The results indicate a promising therapeut...

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Impacto 2

Primary hyperparathyroidism unmasking after dienogest-altered estrogen dynamics: implications for calcium homeostasis.

Publicado: 2026-08-01

JCEM case reports

Medical Digest Indexado: 2026-07-14

This case report discusses a 33-year-old woman with suspected parathyroid adenoma and normocalcemic primary hyperparathyroidism (PHPT). After starting dienogest for menorrhagia, she experienced increased PTH levels and mild hypercalcemia. Imaging confirmed the parathyroid adenoma, which was resec...

Leer en PubMed
Impacto 1

Pragmatic Clinical Trial of Fostamatinib as Second-Line Therapy in Adult Patients With Immune Thrombocytopenia and Insufficient Response to Prior Therapy: The Fostamatinib FORTE Trial.

Publicado: 2026-08-01

EJHaem

Medical Digest Indexado: 2026-07-13

(No abstract provided)

Leer en PubMed
Impacto 3

Breaching the Blood-Brain Barrier: Evolving Strategies for Central Nervous System Disease in Adult Acute Lymphoblastic Leukemia.

Publicado: 2026-07-13

Current hematologic malignancy reports

Medical Digest Indexado: 2026-07-14

This review addresses the critical role of central nervous system (CNS) involvement in adult acute lymphoblastic leukemia (ALL) and its impact on treatment outcomes. It highlights the effectiveness of modern CNS prophylaxis and the challenges posed by immunotherapy-based regimens, particularly in...

Leer en PubMed
Impacto 3

An ensemble machine learning approach for predicting anemia among under-five children in malaria-endemic sub-Saharan African countries.

Publicado: 2026-07-13

Infectious diseases of poverty

Medical Digest Indexado: 2026-07-14

This study addresses the significant public health issue of anemia in children under five in malaria-endemic sub-Saharan Africa. Utilizing a cross-sectional design with a sample of 21,249, the research developed a machine learning model, specifically XGBoost, which demonstrated high accuracy and ...

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