Tendenze della Ricerca Medica

Le pubblicazioni più impattanti della settimana in 29 specialità, curate dall'IA

Ultimo aggiornamento: 28 lug 2026

Cardiologia5 articoli

Impatto 1

CCaS: A New Conceptual Framework in Cerebrovascular Disease.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Advancing Pediatric Stroke Readiness: Engaging Healthcare Systems to Optimize Care Delivery.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

One Only Half Dies: On Receiving the 2026 ISC Ralph L. Sacco Outstanding Stroke Research Mentor Award.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

The abstract emphasizes the importance of mentorship and knowledge transfer in stroke medicine, highlighting how mentors pass down their knowledge and experience to mentees. It underscores the significance of cultivating the next generation of leaders in this field, suggesting that this process i...

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Impatto 3

Acalabrutinib in Waldenström macroglobulinemia yields durable responses with 5 years of follow-up.

Pubblicato: 2026-07-28

Blood advances

Medical Digest Indicizzato: 2026-07-29

The phase 2 ACE-WM-001 trial assessed acalabrutinib in 106 patients with Waldenström macroglobulinemia, showing overall response rates of 92.9% and 94.6% for treatment-naive and relapsed/refractory cohorts, respectively. Median progression-free survival was not estimable for treatment-naive and 6...

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Impatto 2

Clinical phenotype and patient profile of individuals referred for invasive coronary angiography for chronic coronary syndromes: High prevalence of non-obstructive coronary artery disease and its predictors - a multicenter registry analysis.

Pubblicato: 2026-07-28

Kardiologia polska

Medical Digest Indicizzato: 2026-07-29

This study analyzed 749,235 coronary angiographies from Poland's National Registry of Procedures of Invasive Cardiology database, focusing on trends in non-obstructive coronary artery disease. Findings showed an increase in non-obstructive lesions and a decrease in normal angiograms. Higher body ...

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Oncologia5 articoli

Impatto 1

Clinical features of systemic amyloidosis: a scoping review.

Pubblicato: 2026-07-28

Blood advances

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Nitroalkenes exploit dependence on autophagy-lysosome pathway in PARPi-Resistant triple negative breast cancer.

Pubblicato: 2026-07-28

Cancer letters

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 3

GBP6 maintains mitochondrial bioenergetics to promote immune evasion from NK cells in cervical cancer.

Pubblicato: 2026-07-27

Cell reports

Medical Digest Indicizzato: 2026-07-29

This study identifies GBP6 as a mitochondrial factor associated with aggressive cervical cancer, enriched in high-risk tumors and correlating with poor clinical outcomes. GBP6 knockdown suppresses tumor cell proliferation and promotes cell death by disrupting mitochondrial bioenergetics and induc...

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Impatto 3

Spatiotemporally Ultrasound-Controlled Nanoparticles Reprogramming Immunostimulatory Antigen-Presenting Cancer-Associated Fibroblasts to Enhance Cancer Immunotherapy.

Pubblicato: 2026-07-27

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Medical Digest Indicizzato: 2026-07-29

This study focuses on reprogramming myofibroblastic cancer-associated fibroblasts (CAFs) into immune activated antigen presenting CAFs (apCAFs) as a treatment for fibrotic breast cancer. Using a spatiotemporally ultrasound-controlled nanoparticle, the researchers successfully reprogrammed myCAFs ...

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Impatto 3

Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization.

Pubblicato: 2026-07-27

Journal for immunotherapy of cancer

Medical Digest Indicizzato: 2026-07-29

This study explores the role of mitophagy in cancer immunogenicity, identifying TOMM40 as a gatekeeper of mitochondrial import that restrains mitophagy. Loss of TOMM40 induces mitochondrial dysfunction and hyperactivated mitophagy, converting immune-cold tumors into immune-inflamed states with in...

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Neurologia5 articoli

Impatto 1

Stroke Care in Rural Hospitals: A Critical Problem With Looming Challenges.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Correction to: Care of the Patient With Acute Ischemic Stroke (Endovascular/Intensive Care Unit-Postinterventional Therapy): Update to 2009 Comprehensive Nursing Care Scientific Statement: A Scientific Statement From the American Heart Association.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Evaluation of Dried Plasma Spot-Based Quantification of Glial Fibrillary Acidic Protein as a Disease-Associated Biomarker in Neuromyelitis Optica Spectrum Disorder.

Pubblicato: 2026-07-28

Annals of clinical and translational neurology

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Longitudinal surface-based morphometry changes in the hippocampus in dementia.

Pubblicato: 2026-07-28

Neuropsychologia

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 3

Astrocytic LMP2 Coordinates NF-κB and TGF-β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion.

Pubblicato: 2026-07-27

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Medical Digest Indicizzato: 2026-07-29

This study identifies the immunoproteasome subunit LMP2 as a key regulator of astrocyte reactivity and neuroinflammatory outcomes following ischemic stroke. Using knockout models, researchers found that LMP2 deficiency reduces infarct volume, attenuates neuroinflammation, and improves neurologica...

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Gastroenterologia5 articoli

Impatto 1

Integrative analysis of lactylation patterns reveals prognostic biomarkers and therapeutic targets in pancreatic cancer.

Pubblicato: 2026-07-28

Cancer letters

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Effects of Malnutrition on In-Hospital and Discharge Outcomes Among Young Adults Hospitalized with Gastrointestinal Cancers: National Estimates from the United States.

Pubblicato: 2026-07-27

Journal of gastrointestinal cancer

Medical Digest Indicizzato: 2026-07-29

This study found that protein-energy malnutrition (PEM) affects one in five hospitalizations among young adults with gastrointestinal cancers. PEM was associated with higher in-hospital mortality, longer hospital stays, and increased hospital charges. Adjusted analyses showed PEM was independentl...

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Impatto 2

Transfer learning prediction of 2-year native liver survival in biliary atresia following Kasai portoenterostomy using early perioperative biochemical data up to 3 months postoperatively.

Pubblicato: 2026-07-27

Pediatric surgery international

Medical Digest Indicizzato: 2026-07-29

This study evaluated the use of machine learning models to predict 2-year native liver survival (NLS) in biliary atresia (BA) patients following Kasai portoenterostomy (KPE). Data from 154 BA patients were analyzed using traditional machine learning algorithms, with the random forest model showin...

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Impatto 2

Robotic surgery in the application of gallstones and related diseases: a 26-year bibliometric analysis and emerging research trends.

Pubblicato: 2026-07-27

Journal of robotic surgery

Medical Digest Indicizzato: 2026-07-28

This bibliometric analysis of 126 papers on robotic cholecystectomy for gallstone disease reveals a growing trend in research output, particularly after 2021. The United States leads in research productivity, with a significant shift in focus from conventional laparoscopic management to robotic s...

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Impatto 2

BMSNet: a boundary-guided multi-scale polyp segmentation network.

Pubblicato: 2026-07-27

Biomedical physics & engineering express

Medical Digest Indicizzato: 2026-07-28

This study introduces BMSNet, a boundary-guided multi-scale network for accurate polyp segmentation in colonoscopy images. The method uses a Scale-Aware Modulation Meets Transformer-T backbone and includes a boundary prediction module and a boundary-guided feature enhancement module. BMSNet achie...

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Pneumologia5 articoli

Impatto 1

Virtual screening and experimental validation of a METTL3-targeting peptide with

Pubblicato: 2026-12-01

Journal of enzyme inhibition and medicinal chemistry

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 3

Extracellular matrix stiffness orchestrates NETs formation and mTOR-Driven metabolic reprogramming in lung cancer.

Pubblicato: 2026-07-28

Cancer letters

Medical Digest Indicizzato: 2026-07-29

This study highlights the role of neutrophil extracellular traps (NETs) in lung cancer progression, particularly in high-stiffness tumor niches. Using AFM and mIF, the researchers demonstrated a spatial correlation between NETs formation and ECM stiffness, suggesting that targeting NETs could imp...

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Impatto 1

Human Bocavirus Detection in Hospitalized Children With Pneumonia: Findings From Regional Multicenter Surveillance in Saitama, Japan.

Pubblicato: 2026-07-28

The Pediatric infectious disease journal

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Rhinovirus: Too Bad to Be True.

Pubblicato: 2026-07-28

The Pediatric infectious disease journal

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Pediatric Melioidosis.

Pubblicato: 2026-07-28

The Pediatric infectious disease journal

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Endocrinologia5 articoli

Impatto 1

[Practical application of the captopril challenge test for diagnosing primary aldosteronism].

Pubblicato: 2026-07-28

Zhonghua yi xue za zhi

Medical Digest Indicizzato: 2026-07-29

(Abstract too short for summarization)

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Impatto 1

[The impact of dietary sodium intake on therapeutic efficacy and short-term renal injury in patients after treatment for primary aldosteronism].

Pubblicato: 2026-07-28

Zhonghua yi xue za zhi

Medical Digest Indicizzato: 2026-07-29

(Abstract too short for summarization)

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Impatto 1

Dose-dependent effects of oral semaglutide on arterial stiffness and the additive role of SGLT-2 inhibitors in type 2 diabetes.

Pubblicato: 2026-07-28

British journal of clinical pharmacology

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Beyond Siloed Care: The Promise and Challenge of Cardiovascular-Kidney-Metabolic Syndrome.

Pubblicato: 2026-07-28

Circulation

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 2

Visceral adiposity and lipid-related metabolic markers in normal-weight adolescent girls with polycystic ovary syndrome.

Pubblicato: 2026-07-27

European journal of pediatrics

Medical Digest Indicizzato: 2026-07-29

This study found that normal-weight adolescents with polycystic ovary syndrome (PCOS) have greater visceral adiposity compared to healthy controls, even after adjusting for BMI percentile. Triglycerides and the TG/HDL-C ratio were higher in the PCOS group but should be interpreted cautiously in r...

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Nefrologia5 articoli

Impatto 2

Real-world management of dialysis-requiring acute kidney injury in Italy: a national survey of nephrology centers.

Pubblicato: 2026-07-28

Journal of nephrology

Medical Digest Indicizzato: 2026-07-29

This study assessed the care of dialysis-requiring acute kidney injury (AKI-D) across Italy, revealing that AKI-D accounts for 20% to over 60% of dialysis-unit activity. Kidney replacement therapy is often provided outside nephrology wards, primarily in cardiac ICUs and emergency departments. Con...

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Impatto 1

Multimodal ultrasound in renal transplantation: a pictorial essay on graft complications.

Pubblicato: 2026-07-28

Journal of ultrasound

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Robot-assisted versus open kidney transplantation: an umbrella review of systematic reviews and meta-analyses.

Pubblicato: 2026-07-27

Journal of robotic surgery

Medical Digest Indicizzato: 2026-07-28

This umbrella review compared robot-assisted kidney transplantation (RAKT) and open kidney transplantation (OKT) using systematic reviews and meta-analyses. RAKT showed better perioperative outcomes such as reduced blood loss and surgical site infections but open surgery had advantages in certain...

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Impatto 1

Seasonality of acute kidney injury incidence in Japanese outpatients.

Pubblicato: 2026-07-27

Scientific reports

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Stable by what criteria? The need to define the measurement window for immediate postoperative renal pulsatility index.

Pubblicato: 2026-07-27

Journal of clinical anesthesia

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Reumatologia5 articoli

Impatto 2

Interleukin-2 is associated with cytopenias in systemic lupus erythematosus.

Pubblicato: 2026-12-31

Autoimmunity

Medical Digest Indicizzato: 2026-07-27

This study involving 235 patients with systemic lupus erythematosus (SLE) found that lower serum interleukin-2 (IL-2) levels were associated with specific hematological abnormalities, including anemia, leukopenia, and lymphopenia. Using multivariate regression analysis, the study identified signi...

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Impatto 2

Probiotic

Pubblicato: 2026-12-31

Gut microbes

Medical Digest Indicizzato: 2026-07-24

This study highlights the role of gut microbiota dysbiosis and host protein glycosylation in the immune signaling involved in the progression of rheumatoid arthritis (RA).

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Impatto 1

Clinicopathological Features of Lupus Erythematosus Panniculitis (LEP): A Retrospective Analysis of 54 Cases.

Pubblicato: 2026-08-01

Health science reports

Medical Digest Indicizzato: 2026-07-28

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.

Pubblicato: 2026-07-27

The Analyst

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Wedelolactone alleviates rheumatoid arthritis by gut microbiota-dependent immunomodulation and p53-mediated inhibition of fibroblast-like synoviocytes.

Pubblicato: 2026-07-25

Phytomedicine : international journal of phytotherapy and phytopharmacology

Medical Digest Indicizzato: 2026-07-26

(Summary generation failed. Please refer to the original article.)

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Infettivologia5 articoli

Impatto 2

Biofilm-mediated antibiotic tolerance in bacterial pathogens: Integrated molecular networks and novel therapeutic avenues.

Pubblicato: 2026-12-01

Virulence

Medical Digest Indicizzato: 2026-07-29

This review discusses the formation process of biofilms, mechanisms of antibiotic tolerance and resistance, and new intervention approaches. Biofilms, with their stable structure and protective mechanisms, pose a significant challenge in eradicating clinical infections. The review highlights the ...

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Impatto 1

[Medium-to long-term outcomes of total hip arthroplasty for sequelae of hip infection].

Pubblicato: 2026-07-28

Zhonghua wai ke za zhi [Chinese journal of surgery]

Medical Digest Indicizzato: 2026-07-29

(Abstract too short for summarization)

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Impatto 3

Empiric tuberculosis treatment in hospitalised adults with advanced HIV disease in Africa: applying the therapeutic threshold to clinical practice.

Pubblicato: 2026-07-27

The Lancet. Infectious diseases

Medical Digest Indicizzato: 2026-07-29

In sub-Saharan Africa, advanced HIV patients hospitalized with high mortality rates often have undiagnosed tuberculosis. Despite concerns about toxicity and drug interactions, short-term empiric antituberculous therapy appears safe and may improve survival in high-risk patients. A paradigm shift ...

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Impatto 2

Phylogenetic Groups and Antibiotic Resistance Genes of Escherichia coli isolated from Food and Humans in Ouagadougou, Burkina Faso.

Pubblicato: 2026-07-27

Current microbiology

Medical Digest Indicizzato: 2026-07-29

This study analyzed 144 E. coli strains to investigate the correlation between phylogenetic groups and antibiotic resistance. Clinical isolates showed high resistance to cephalosporins and fluoroquinolones, while food-derived strains had lower resistance levels. Phylogroup A had the highest preva...

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Impatto 1

Transcriptional Profiling of Hypo- and Hypervirulent Mycobacterium tuberculosis Isolates Characterised by Differential Expression of the Moa3 Operon.

Pubblicato: 2026-07-27

Current microbiology

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Ematologia5 articoli

Impatto 1

Characteristics of Clinical Response in Patients With Chronic Myeloid Leukemia With an

Pubblicato: 2026-08-01

EJHaem

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Intravascular Large B-Cell Lymphoma Masquerading as Cerebral Amyloid Angiopathy-Related Inflammation.

Pubblicato: 2026-08-01

Stroke

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 2

Antifungal Use in Pediatric Hematology-Oncology and Bone Marrow Transplantation Units in Greece.

Pubblicato: 2026-07-28

The Pediatric infectious disease journal

Medical Digest Indicizzato: 2026-07-29

This study highlights the extensive and heterogeneous use of antifungal agents in pediatric oncology and hematopoietic stem cell transplantation settings, with a heavy reliance on prophylactic and empiric strategies and minimal targeted therapy. The findings underscore the need for structured ant...

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Impatto 2

[Expert consensus on the clinical diagnosis and management of mucormycosis in patients with hematologic malignancies and undergoing hematopoietic stem cell transplantation (2026 edition)].

Pubblicato: 2026-07-28

Zhonghua yi xue za zhi

Medical Digest Indicizzato: 2026-07-29

The incidence of mucormycosis is increasing among patients with hematologic malignancies and those undergoing hematopoietic stem cell transplantation in China. A consensus led by the Mycology Committee of the Chinese Medical Education Association, involving 23 experts, was developed to address th...

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Impatto 1

AVD for older patients with classical Hodgkin lymphoma.

Pubblicato: 2026-07-28

Blood advances

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Psichiatria5 articoli

Impatto 1

Severe floods increase long-term opioid overdose mortality.

Pubblicato: 2026-07-28

Proceedings of the National Academy of Sciences of the United States of America

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Symptom networks of therapy-seeking individuals with comorbid psychosis and PTSD.

Pubblicato: 2026-07-28

Psychological medicine

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

When children shape their families: Evocative effects analysis of 40,000 trios from the Norwegian Mother, Father and Child Cohort Study.

Pubblicato: 2026-07-28

Proceedings of the National Academy of Sciences of the United States of America

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Characterisation of alogia in people with schizophrenia using natural language processing. a comparative study with a group of people with bipolar disorder.

Pubblicato: 2026-07-27

Cognitive neuropsychiatry

Medical Digest Indicizzato: 2026-07-29

This study evaluated cognitive functioning and linguistic measures in patients with schizophrenia, bipolar disorder, and healthy controls. Participants with schizophrenia showed lower verbal production and reduced sentence complexity compared to healthy controls, while those with bipolar disorder...

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Impatto 2

Machine learning reveals a multimodal, transdiagnostic signature of emotion dysregulation vulnerability across patients, offspring, and controls.

Pubblicato: 2026-07-27

Molecular psychiatry

Medical Digest Indicizzato: 2026-07-29

This study used a transdiagnostic framework to identify early markers of emotion dysregulation (ED) in high-risk populations. A total of 237 participants completed a multimodal assessment. Principal component analysis (PCA) identified eight components, with two significantly differing between gro...

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Dermatologia5 articoli

Impatto 1

Spatial T lymphocyte infiltration into the primary melanoma tumor associates with survival.

Pubblicato: 2026-07-28

Melanoma research

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Lipid-based nanocarriers as versatile platforms for curcumin delivery in photodynamic therapy of skin cancer.

Pubblicato: 2026-07-27

International journal of pharmaceutics

Medical Digest Indicizzato: 2026-07-29

This study developed three curcumin lipid nanoparticles for non-melanoma skin cancer treatment. The nanoparticles showed improved skin penetration and enhanced cytotoxic and phototoxic effects compared to free curcumin. Specifically, A1Cur exhibited a hexagonal liquid-crystalline phase and demons...

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Impatto 2

Reporting of Racial and Ethnic Diversity in Dermatology Clinical Trials Involving Canada, 2020 to 2025: A Systematic Review.

Pubblicato: 2026-07-27

Journal of cutaneous medicine and surgery

Medical Digest Indicizzato: 2026-07-28

This study evaluated the reporting of race, ethnicity, and skin type in Canadian dermatology RCTs published between 2020 and 2025. Among 99 trials with 36,178 participants, race was reported in 93%, ethnicity in 39%, and Fitzpatrick skin type in 10%. Detailed racial or ethnic categories were pres...

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Impatto 2

Oncolytic Virotherapy, Long Stalled, Nears Second Approval.

Pubblicato: 2026-07-27

Cancer discovery

Medical Digest Indicizzato: 2026-07-28

This study highlights the challenges in advancing oncolytic viruses for cancer treatment, with T-VEC being the first approved and RP1 as the next candidate for melanoma. Issues such as flawed trial designs, mistimed drug combinations, tumor defenses, and delivery challenges have hindered progress...

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Impatto 1

Palmoplantar pustulosis is associated with greater burden and impaired quality of life compared to psoriasis only: findings from a cross-sectional study within the Danish Skin Cohort.

Pubblicato: 2026-07-27

Journal of the American Academy of Dermatology

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Oftalmologia5 articoli

Impatto 3

Innovations in glaucoma treatment: development and testing of a novel self-adjustable implant for effective pressure regulation.

Pubblicato: 2026-07-27

Microsystems & nanoengineering

Medical Digest Indicizzato: 2026-07-29

This study introduces a compact, passive glaucoma implant designed to dynamically modulate hydraulic resistance and maintain intraocular pressure within physiological ranges. The implant effectively regulates pressure, mitigates early hypotony, and adapts to increasing downstream resistance. Ex v...

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Impatto 2

Ocular Response Analyzer versus Goldmann Applanation Tonometry in a Population-based Sample: The Thessaloniki Eye Study.

Pubblicato: 2026-07-27

American journal of ophthalmology

Medical Digest Indicizzato: 2026-07-29

This study compared corneal-compensated intraocular pressure (IOPcc) with Goldmann applanation tonometry (GAT-IOP) in an elderly cohort. Using data from the Thessaloniki Eye Study, it found that IOPcc was on average 2.75 mmHg higher than GAT-IOP. The prevalence of ocular hypertension increased fr...

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Impatto 2

Real-World Outcomes of Faricimab for Polypoidal Choroidal Vasculopathy in a Multi-ethnic Cohort: A 12-Month Retrospective Study.

Pubblicato: 2026-07-27

Ophthalmology and therapy

Medical Digest Indicizzato: 2026-07-29

This retrospective cohort study evaluated the 12-month outcomes of faricimab treatment for polypoidal choroidal vasculopathy (PCV) in a multi-ethnic cohort. In treatment-naïve eyes, visual acuity improved by +6.8 letters (P < 0.01) and CST reduced by -54 µm (P < 0.01). In treatment-experienced ey...

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Impatto 2

Efficacy and safety at 12 months of PRESERFLO® combined with DuraGen® and morphological evaluation using AS-OCT.

Pubblicato: 2026-07-27

Archivos de la Sociedad Espanola de Oftalmologia

Medical Digest Indicizzato: 2026-07-29

This prospective study evaluated the efficacy and safety of PRESERFLO® implantation combined with 0.04% MMC and DuraGen® in 50 eyes with moderate or severe glaucoma. The mean preoperative intraocular pressure (IOP) was 26.8 ± 7.1 mmHg, which decreased to 13.1 ± 4.5 mmHg, a reduction of 47.9% (p <...

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Impatto 2

Association between Pre-diagnostic Macular Thickness With Risk of Age-related Macular Degeneration.

Pubblicato: 2026-07-27

Retina (Philadelphia, Pa.)

Medical Digest Indicizzato: 2026-07-29

This study involving 40,078 participants from the UK Biobank aimed to determine if specific pre-diagnostic macular thickness patterns are linked to an increased risk of age-related macular degeneration (AMD). Using optical coherence tomography (OCT) imaging, two distinct macular thickness profile...

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Pediatria5 articoli

Impatto 1

Artificial intelligence in pediatric medical genetics and genomics.

Pubblicato: 2026-07-28

Current opinion in pediatrics

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

A Multitask Deep Learning Model for Pediatric Echocardiography Analysis.

Pubblicato: 2026-07-28

Circulation

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Real-world effectiveness of maternal genetically inactivated acellular pertussis vaccination in protecting infants under three months of age: a case-control study using concurrent community-based and test-negative controls.

Pubblicato: 2026-07-27

Infection

Medical Digest Indicizzato: 2026-07-29

This study evaluated the effectiveness of maternal aP vaccination in preventing pertussis in infants during an outbreak in Thailand. The case-control study included 33 symptomatic cases and 330 asymptomatic controls. Results showed that maternal vaccination significantly reduced the risk of pertu...

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Impatto 2

Prevalence of Post-Intensive Care Syndrome in Paediatrics in children with CHD and association with health-related quality of life outcomes.

Pubblicato: 2026-07-27

Cardiology in the young

Medical Digest Indicizzato: 2026-07-28

This study evaluated Post-intensive Care Syndrome in Paediatrics in CHD patients aged 5-18 years with at least one cardiac ICU admission. Using physical, cognitive, social, and emotional questionnaires, 80% of the 117 patients were found to have the syndrome, with 36% physical, 70% cognitive, 26%...

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Impatto 2

Association between hyperchloremia and outcomes of children admitted to the pediatric intensive care unit (PICU) with diabetic ketoacidosis (DKA).

Pubblicato: 2026-07-27

Journal of pediatric endocrinology & metabolism : JPEM

Medical Digest Indicizzato: 2026-07-28

This retrospective cohort study of 162 pediatric patients with diabetic ketoacidosis (DKA) found that hyperchloremia, present in 81.5% of patients, is associated with longer DKA resolution time, slower bicarbonate rise, and longer PICU stay. Hyperchloremia was predicted by lower body weight and t...

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Medicina d'Emergenza5 articoli

Impatto 1

Assessing readiness for large-scale combat operations across the full spectrum of medical and surgical capabilities.

Pubblicato: 2026-08-01

The journal of trauma and acute care surgery

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Time Is Aorta: Can Artificial Intelligence Improve Surgical Timelines in Acute Type A Aortic Dissection? A Comprehensive Review.

Pubblicato: 2026-08-01

Health science reports

Medical Digest Indicizzato: 2026-07-28

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Isolation Before Manipulation: A Stepwise Strategy for Emergency Multivisceral Resection of Colosplenic Fistula.

Pubblicato: 2026-07-28

The American surgeon

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 2

The current evidence of 'peer-led' cardiopulmonary resuscitation training: a scoping review.

Pubblicato: 2026-07-27

Clinical and experimental emergency medicine

Medical Digest Indicizzato: 2026-07-29

This scoping review aimed to explore existing evidence on peer-led CPR training across various populations and settings. A total of 37 studies were included, identifying four peer-training models. The review found that peer-led training often achieved similar educational outcomes to professional ...

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Impatto 2

Neglected traumatic hip dislocation: a systematic review of case reports and case series on management, outcomes, and complications.

Pubblicato: 2026-07-27

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Medical Digest Indicizzato: 2026-07-29

This systematic review evaluated management strategies for neglected traumatic hip dislocation (NTHD), focusing on functional outcomes and complications. Twenty-one studies with 200 patients were analyzed. Open reduction is viable for dislocations less than 3 months, while THA is most reliable fo...

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Chirurgia5 articoli

Impatto 1

[Effects of a structured language intervention based on predictive coding theory on patient experience and completion status of conventional gastroscopy].

Pubblicato: 2026-07-28

Zhonghua yi xue za zhi

Medical Digest Indicizzato: 2026-07-29

(Abstract too short for summarization)

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Impatto 1

Development and Implementation of a Tiered Mentorship Program in a General Surgery Residency.

Pubblicato: 2026-07-27

Journal of surgical education

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Renal paratransplant hernia: uncommon internal hernia with obscure and delayed presentation.

Pubblicato: 2026-07-27

Polish archives of internal medicine

Medical Digest Indicizzato: 2026-07-29

(No abstract provided)

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Impatto 1

Cholecystectomy before diagnosis of primary sclerosing cholangitis is associated with markedly worsened transplant free survival.

Pubblicato: 2026-07-27

JHEP reports : innovation in hepatology

Medical Digest Indicizzato: 2026-07-29

(Summary generation failed. Please refer to the original article.)

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Impatto 1

Model-based design and placement analysis for epidural cortical stimulation.

Pubblicato: 2026-07-27

Journal of neural engineering

Medical Digest Indicizzato: 2026-07-28

(No abstract provided)

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Ostetricia e Ginecologia5 articoli

Impatto 3

The global impact of female infertility: regional disparities and future projections from the GBD 2021 study.

Pubblicato: 2026-12-31

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

Medical Digest Indicizzato: 2026-07-24

This study highlights the significant rise in female infertility globally, with cases increasing by 84.4% from 1990 to 2021, reaching 110.09 million. The age-standardized prevalence rate is also on the rise, particularly in high SDI regions, which show the fastest growth. Projections indicate tha...

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Impatto 3

Placental 3D Doppler and uterine artery Doppler for predicting adverse outcomes in placenta accreta: a retrospective cohort study.

Pubblicato: 2026-12-01

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Medical Digest Indicizzato: 2026-07-25

This study investigates the predictive value of ultrasound measures in patients with placenta accreta spectrum (PAS) for adverse pregnancy outcomes (APOs). Among 180 women with PAS, 42.22% experienced complications. The study found that those with complications exhibited higher placental blood fl...

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Impatto 2

Oocyte maturation and pregnancy outcomes in relation to gonadotropin duration in antagonist cycles.

Pubblicato: 2026-12-01

Annals of medicine

Medical Digest Indicizzato: 2026-07-26

This retrospective study of 9372 GnRH antagonist cycles found that gonadotropin stimulation duration is associated with oocyte maturation and pregnancy outcomes, even after adjusting for confounders. The optimal duration for achieving the highest likelihood of clinical pregnancy and live birth is...

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Impatto 1

Re-evaluating low-molecular-weight heparin use in recurrent missed miscarriage: current evidence and future directions.

Pubblicato: 2026-12-01

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Medical Digest Indicizzato: 2026-07-26

(Summary generation failed. Please refer to the original article.)

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Impatto 2

Managing TRAP Sequence Conservatively: A Case Report of Full-Term Pregnancy With Favorable Outcome.

Pubblicato: 2026-08-01

Clinical case reports

Medical Digest Indicizzato: 2026-07-25

Acardiac twinning, or TRAP sequence, is a rare condition in monochorionic twins characterized by severe malformation of one twin due to abnormal placental blood flow. In a case study of a 30-year-old woman, an acephalus acardiac twin was diagnosed during the second trimester. The prognosis for th...

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