Impatto 1
Clinical features of systemic amyloidosis: a scoping review.
Pubblicato: 2026-07-28
Blood advances
Medical Digest Indicizzato: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Leggi su PubMedOncologia5 articoli
Impatto 1
Nitroalkenes exploit dependence on autophagy-lysosome pathway in PARPi-Resistant triple negative breast cancer.
Pubblicato: 2026-07-28
Cancer letters
Medical Digest Indicizzato: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Leggi su PubMedImpatto 3
GBP6 maintains mitochondrial bioenergetics to promote immune evasion from NK cells in cervical cancer.
Pubblicato: 2026-07-27
Cell reports
Medical Digest Indicizzato: 2026-07-29
This study identifies GBP6 as a mitochondrial factor associated with aggressive cervical cancer, enriched in high-risk tumors and correlating with poor clinical outcomes. GBP6 knockdown suppresses tumor cell proliferation and promotes cell death by disrupting mitochondrial bioenergetics and induc...
Leggi su PubMedImpatto 3
Spatiotemporally Ultrasound-Controlled Nanoparticles Reprogramming Immunostimulatory Antigen-Presenting Cancer-Associated Fibroblasts to Enhance Cancer Immunotherapy.
Pubblicato: 2026-07-27
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Medical Digest Indicizzato: 2026-07-29
This study focuses on reprogramming myofibroblastic cancer-associated fibroblasts (CAFs) into immune activated antigen presenting CAFs (apCAFs) as a treatment for fibrotic breast cancer. Using a spatiotemporally ultrasound-controlled nanoparticle, the researchers successfully reprogrammed myCAFs ...
Leggi su PubMedImpatto 3
Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization.
Pubblicato: 2026-07-27
Journal for immunotherapy of cancer
Medical Digest Indicizzato: 2026-07-29
This study explores the role of mitophagy in cancer immunogenicity, identifying TOMM40 as a gatekeeper of mitochondrial import that restrains mitophagy. Loss of TOMM40 induces mitochondrial dysfunction and hyperactivated mitophagy, converting immune-cold tumors into immune-inflamed states with in...
Leggi su PubMed