重要度 1
CCaS: A New Conceptual Framework in Cerebrovascular Disease.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む循環器内科5 件
重要度 1
Advancing Pediatric Stroke Readiness: Engaging Healthcare Systems to Optimize Care Delivery.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
One Only Half Dies: On Receiving the 2026 ISC Ralph L. Sacco Outstanding Stroke Research Mentor Award.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
要約は、脳卒中医療におけるメンターシップと知識移転の重要性を強調し、メンターが知識と経験をメンティーに引き継ぐ方法を強調しています。この分野における次世代のリーダーを育成することの重要性を強調し、このプロセスが脳卒中医療の継続的な進歩にとって不可欠であることを示唆しています。 要約は、脳卒中医療におけるメンターシップと知識移転の重要性を強調し、メンターが知識と経験をメンティーに引き継ぐ方法を強調しています。次世代のリーダーをこの分野で育成することの重要性を強調し、このプロセスが脳卒中医療の継続的な進歩にとって不可欠であることを示唆しています。
PubMedで読む重要度 3
Acalabrutinib in Waldenström macroglobulinemia yields durable responses with 5 years of follow-up.
論文発表日: 2026-07-28
Blood advances
Medical Digest 収録日: 2026-07-29
ACE-WM-001第2相試験は、ワルデンストロームマクログロブリン血症の106人の患者においてアカラブルチニブを評価し、治療未経験群と再発/難治性群でそれぞれ全体的な奏功率が92.9%と94.6%であったことを示しました。治療未経験群の無進行生存期間中央値は推定不可能であり、再発/難治性群は67.5ヶ月でした。治療未経験群の奏功期間中央値は達成されず、再発/難治性群は64.7ヶ月でした。両群において無進行生存期間中央値は達成されませんでした。5年間のフォローアップで、アカラブルチニブはその有効性と安全性プロファイルを維持しました。
PubMedで読む重要度 2
Clinical phenotype and patient profile of individuals referred for invasive coronary angiography for chronic coronary syndromes: High prevalence of non-obstructive coronary artery disease and its predictors - a multicenter registry analysis.
論文発表日: 2026-07-28
Kardiologia polska
Medical Digest 収録日: 2026-07-29
This study analyzed 749,235 coronary angiographies from Poland's National Registry of Procedures of Invasive Cardiology database, focusing on trends in non-obstructive coronary artery disease. Findings showed an increase in non-obstructive lesions and a decrease in normal angiograms. Higher body ...
PubMedで読む腫瘍内科5 件
重要度 1
Clinical features of systemic amyloidosis: a scoping review.
論文発表日: 2026-07-28
Blood advances
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Nitroalkenes exploit dependence on autophagy-lysosome pathway in PARPi-Resistant triple negative breast cancer.
論文発表日: 2026-07-28
Cancer letters
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 3
GBP6 maintains mitochondrial bioenergetics to promote immune evasion from NK cells in cervical cancer.
論文発表日: 2026-07-27
Cell reports
Medical Digest 収録日: 2026-07-29
This study identifies GBP6 as a mitochondrial factor associated with aggressive cervical cancer, enriched in high-risk tumors and correlating with poor clinical outcomes. GBP6 knockdown suppresses tumor cell proliferation and promotes cell death by disrupting mitochondrial bioenergetics and induc...
PubMedで読む重要度 3
Spatiotemporally Ultrasound-Controlled Nanoparticles Reprogramming Immunostimulatory Antigen-Presenting Cancer-Associated Fibroblasts to Enhance Cancer Immunotherapy.
論文発表日: 2026-07-27
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Medical Digest 収録日: 2026-07-29
This study focuses on reprogramming myofibroblastic cancer-associated fibroblasts (CAFs) into immune activated antigen presenting CAFs (apCAFs) as a treatment for fibrotic breast cancer. Using a spatiotemporally ultrasound-controlled nanoparticle, the researchers successfully reprogrammed myCAFs ...
PubMedで読む重要度 3
Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization.
論文発表日: 2026-07-27
Journal for immunotherapy of cancer
Medical Digest 収録日: 2026-07-29
This study explores the role of mitophagy in cancer immunogenicity, identifying TOMM40 as a gatekeeper of mitochondrial import that restrains mitophagy. Loss of TOMM40 induces mitochondrial dysfunction and hyperactivated mitophagy, converting immune-cold tumors into immune-inflamed states with in...
PubMedで読む神経内科5 件
重要度 1
Stroke Care in Rural Hospitals: A Critical Problem With Looming Challenges.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Correction to: Care of the Patient With Acute Ischemic Stroke (Endovascular/Intensive Care Unit-Postinterventional Therapy): Update to 2009 Comprehensive Nursing Care Scientific Statement: A Scientific Statement From the American Heart Association.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Evaluation of Dried Plasma Spot-Based Quantification of Glial Fibrillary Acidic Protein as a Disease-Associated Biomarker in Neuromyelitis Optica Spectrum Disorder.
論文発表日: 2026-07-28
Annals of clinical and translational neurology
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Longitudinal surface-based morphometry changes in the hippocampus in dementia.
論文発表日: 2026-07-28
Neuropsychologia
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 3
Astrocytic LMP2 Coordinates NF-κB and TGF-β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion.
論文発表日: 2026-07-27
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Medical Digest 収録日: 2026-07-29
This study identifies the immunoproteasome subunit LMP2 as a key regulator of astrocyte reactivity and neuroinflammatory outcomes following ischemic stroke. Using knockout models, researchers found that LMP2 deficiency reduces infarct volume, attenuates neuroinflammation, and improves neurologica...
PubMedで読む消化器内科5 件
重要度 1
Integrative analysis of lactylation patterns reveals prognostic biomarkers and therapeutic targets in pancreatic cancer.
論文発表日: 2026-07-28
Cancer letters
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Effects of Malnutrition on In-Hospital and Discharge Outcomes Among Young Adults Hospitalized with Gastrointestinal Cancers: National Estimates from the United States.
論文発表日: 2026-07-27
Journal of gastrointestinal cancer
Medical Digest 収録日: 2026-07-29
This study found that protein-energy malnutrition (PEM) affects one in five hospitalizations among young adults with gastrointestinal cancers. PEM was associated with higher in-hospital mortality, longer hospital stays, and increased hospital charges. Adjusted analyses showed PEM was independentl...
PubMedで読む重要度 2
Transfer learning prediction of 2-year native liver survival in biliary atresia following Kasai portoenterostomy using early perioperative biochemical data up to 3 months postoperatively.
論文発表日: 2026-07-27
Pediatric surgery international
Medical Digest 収録日: 2026-07-29
This study evaluated the use of machine learning models to predict 2-year native liver survival (NLS) in biliary atresia (BA) patients following Kasai portoenterostomy (KPE). Data from 154 BA patients were analyzed using traditional machine learning algorithms, with the random forest model showin...
PubMedで読む重要度 2
Robotic surgery in the application of gallstones and related diseases: a 26-year bibliometric analysis and emerging research trends.
論文発表日: 2026-07-27
Journal of robotic surgery
Medical Digest 収録日: 2026-07-28
This bibliometric analysis of 126 papers on robotic cholecystectomy for gallstone disease reveals a growing trend in research output, particularly after 2021. The United States leads in research productivity, with a significant shift in focus from conventional laparoscopic management to robotic s...
PubMedで読む重要度 2
BMSNet: a boundary-guided multi-scale polyp segmentation network.
論文発表日: 2026-07-27
Biomedical physics & engineering express
Medical Digest 収録日: 2026-07-28
この研究では、大腸内視鏡画像におけるポリプの正確な分割のための境界ガイド付きマルチスケールネットワークであるBMSNetを紹介しています。この方法は、Scale-Aware Modulation Meets Transformer-Tのバックボーンを使用し、境界予測モジュールと境界ガイド付き特徴強化モジュールを含んでいます。BMSNetは5つのベンチマークデータセットで高いDiceスコアを達成し、コンピューター支援診断と早期大腸がんスクリーニングの有効性が示されています。
PubMedで読む呼吸器内科5 件
重要度 1
Virtual screening and experimental validation of a METTL3-targeting peptide with
論文発表日: 2026-12-01
Journal of enzyme inhibition and medicinal chemistry
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 3
Extracellular matrix stiffness orchestrates NETs formation and mTOR-Driven metabolic reprogramming in lung cancer.
論文発表日: 2026-07-28
Cancer letters
Medical Digest 収録日: 2026-07-29
This study highlights the role of neutrophil extracellular traps (NETs) in lung cancer progression, particularly in high-stiffness tumor niches. Using AFM and mIF, the researchers demonstrated a spatial correlation between NETs formation and ECM stiffness, suggesting that targeting NETs could imp...
PubMedで読む重要度 1
Human Bocavirus Detection in Hospitalized Children With Pneumonia: Findings From Regional Multicenter Surveillance in Saitama, Japan.
論文発表日: 2026-07-28
The Pediatric infectious disease journal
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Rhinovirus: Too Bad to Be True.
論文発表日: 2026-07-28
The Pediatric infectious disease journal
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Pediatric Melioidosis.
論文発表日: 2026-07-28
The Pediatric infectious disease journal
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む糖尿病・内分泌内科5 件
重要度 1
[Practical application of the captopril challenge test for diagnosing primary aldosteronism].
論文発表日: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest 収録日: 2026-07-29
(Abstract too short for summarization)
PubMedで読む重要度 1
[The impact of dietary sodium intake on therapeutic efficacy and short-term renal injury in patients after treatment for primary aldosteronism].
論文発表日: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest 収録日: 2026-07-29
(Abstract too short for summarization)
PubMedで読む重要度 1
Dose-dependent effects of oral semaglutide on arterial stiffness and the additive role of SGLT-2 inhibitors in type 2 diabetes.
論文発表日: 2026-07-28
British journal of clinical pharmacology
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Beyond Siloed Care: The Promise and Challenge of Cardiovascular-Kidney-Metabolic Syndrome.
論文発表日: 2026-07-28
Circulation
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 2
Visceral adiposity and lipid-related metabolic markers in normal-weight adolescent girls with polycystic ovary syndrome.
論文発表日: 2026-07-27
European journal of pediatrics
Medical Digest 収録日: 2026-07-29
This study found that normal-weight adolescents with polycystic ovary syndrome (PCOS) have greater visceral adiposity compared to healthy controls, even after adjusting for BMI percentile. Triglycerides and the TG/HDL-C ratio were higher in the PCOS group but should be interpreted cautiously in r...
PubMedで読む腎臓内科5 件
重要度 2
Real-world management of dialysis-requiring acute kidney injury in Italy: a national survey of nephrology centers.
論文発表日: 2026-07-28
Journal of nephrology
Medical Digest 収録日: 2026-07-29
This study assessed the care of dialysis-requiring acute kidney injury (AKI-D) across Italy, revealing that AKI-D accounts for 20% to over 60% of dialysis-unit activity. Kidney replacement therapy is often provided outside nephrology wards, primarily in cardiac ICUs and emergency departments. Con...
PubMedで読む重要度 1
Multimodal ultrasound in renal transplantation: a pictorial essay on graft complications.
論文発表日: 2026-07-28
Journal of ultrasound
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Robot-assisted versus open kidney transplantation: an umbrella review of systematic reviews and meta-analyses.
論文発表日: 2026-07-27
Journal of robotic surgery
Medical Digest 収録日: 2026-07-28
This umbrella review compared robot-assisted kidney transplantation (RAKT) and open kidney transplantation (OKT) using systematic reviews and meta-analyses. RAKT showed better perioperative outcomes such as reduced blood loss and surgical site infections but open surgery had advantages in certain...
PubMedで読む重要度 1
Seasonality of acute kidney injury incidence in Japanese outpatients.
論文発表日: 2026-07-27
Scientific reports
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Stable by what criteria? The need to define the measurement window for immediate postoperative renal pulsatility index.
論文発表日: 2026-07-27
Journal of clinical anesthesia
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読むリウマチ・膠原病内科5 件
重要度 2
Interleukin-2 is associated with cytopenias in systemic lupus erythematosus.
論文発表日: 2026-12-31
Autoimmunity
Medical Digest 収録日: 2026-07-27
This study involving 235 patients with systemic lupus erythematosus (SLE) found that lower serum interleukin-2 (IL-2) levels were associated with specific hematological abnormalities, including anemia, leukopenia, and lymphopenia. Using multivariate regression analysis, the study identified signi...
PubMedで読む重要度 2
Probiotic
論文発表日: 2026-12-31
Gut microbes
Medical Digest 収録日: 2026-07-24
この研究では、関節リウマチ（RA）の進行に関与する免疫シグナル伝達における腸内微生物叢の不均衡と宿主タンパク質の糖鎖修飾の役割が示されました。
PubMedで読む重要度 1
Clinicopathological Features of Lupus Erythematosus Panniculitis (LEP): A Retrospective Analysis of 54 Cases.
論文発表日: 2026-08-01
Health science reports
Medical Digest 収録日: 2026-07-28
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.
論文発表日: 2026-07-27
The Analyst
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Wedelolactone alleviates rheumatoid arthritis by gut microbiota-dependent immunomodulation and p53-mediated inhibition of fibroblast-like synoviocytes.
論文発表日: 2026-07-25
Phytomedicine : international journal of phytotherapy and phytopharmacology
Medical Digest 収録日: 2026-07-26
(Summary generation failed. Please refer to the original article.)
PubMedで読む感染症内科5 件
重要度 2
Biofilm-mediated antibiotic tolerance in bacterial pathogens: Integrated molecular networks and novel therapeutic avenues.
論文発表日: 2026-12-01
Virulence
Medical Digest 収録日: 2026-07-29
This review discusses the formation process of biofilms, mechanisms of antibiotic tolerance and resistance, and new intervention approaches. Biofilms, with their stable structure and protective mechanisms, pose a significant challenge in eradicating clinical infections. The review highlights the ...
PubMedで読む重要度 1
[Medium-to long-term outcomes of total hip arthroplasty for sequelae of hip infection].
論文発表日: 2026-07-28
Zhonghua wai ke za zhi [Chinese journal of surgery]
Medical Digest 収録日: 2026-07-29
(Abstract too short for summarization)
PubMedで読む重要度 3
Empiric tuberculosis treatment in hospitalised adults with advanced HIV disease in Africa: applying the therapeutic threshold to clinical practice.
論文発表日: 2026-07-27
The Lancet. Infectious diseases
Medical Digest 収録日: 2026-07-29
In sub-Saharan Africa, advanced HIV patients hospitalized with high mortality rates often have undiagnosed tuberculosis. Despite concerns about toxicity and drug interactions, short-term empiric antituberculous therapy appears safe and may improve survival in high-risk patients. A paradigm shift ...
PubMedで読む重要度 2
Phylogenetic Groups and Antibiotic Resistance Genes of Escherichia coli isolated from Food and Humans in Ouagadougou, Burkina Faso.
論文発表日: 2026-07-27
Current microbiology
Medical Digest 収録日: 2026-07-29
This study analyzed 144 E. coli strains to investigate the correlation between phylogenetic groups and antibiotic resistance. Clinical isolates showed high resistance to cephalosporins and fluoroquinolones, while food-derived strains had lower resistance levels. Phylogroup A had the highest preva...
PubMedで読む重要度 1
Transcriptional Profiling of Hypo- and Hypervirulent Mycobacterium tuberculosis Isolates Characterised by Differential Expression of the Moa3 Operon.
論文発表日: 2026-07-27
Current microbiology
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む血液内科5 件
重要度 1
Characteristics of Clinical Response in Patients With Chronic Myeloid Leukemia With an
論文発表日: 2026-08-01
EJHaem
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Intravascular Large B-Cell Lymphoma Masquerading as Cerebral Amyloid Angiopathy-Related Inflammation.
論文発表日: 2026-08-01
Stroke
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 2
Antifungal Use in Pediatric Hematology-Oncology and Bone Marrow Transplantation Units in Greece.
論文発表日: 2026-07-28
The Pediatric infectious disease journal
Medical Digest 収録日: 2026-07-29
This study highlights the extensive and heterogeneous use of antifungal agents in pediatric oncology and hematopoietic stem cell transplantation settings, with a heavy reliance on prophylactic and empiric strategies and minimal targeted therapy. The findings underscore the need for structured ant...
PubMedで読む重要度 2
[Expert consensus on the clinical diagnosis and management of mucormycosis in patients with hematologic malignancies and undergoing hematopoietic stem cell transplantation (2026 edition)].
論文発表日: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest 収録日: 2026-07-29
The incidence of mucormycosis is increasing among patients with hematologic malignancies and those undergoing hematopoietic stem cell transplantation in China. A consensus led by the Mycology Committee of the Chinese Medical Education Association, involving 23 experts, was developed to address th...
PubMedで読む重要度 1
AVD for older patients with classical Hodgkin lymphoma.
論文発表日: 2026-07-28
Blood advances
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む精神科5 件
重要度 1
Severe floods increase long-term opioid overdose mortality.
論文発表日: 2026-07-28
Proceedings of the National Academy of Sciences of the United States of America
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Symptom networks of therapy-seeking individuals with comorbid psychosis and PTSD.
論文発表日: 2026-07-28
Psychological medicine
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
When children shape their families: Evocative effects analysis of 40,000 trios from the Norwegian Mother, Father and Child Cohort Study.
論文発表日: 2026-07-28
Proceedings of the National Academy of Sciences of the United States of America
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Characterisation of alogia in people with schizophrenia using natural language processing. a comparative study with a group of people with bipolar disorder.
論文発表日: 2026-07-27
Cognitive neuropsychiatry
Medical Digest 収録日: 2026-07-29
This study evaluated cognitive functioning and linguistic measures in patients with schizophrenia, bipolar disorder, and healthy controls. Participants with schizophrenia showed lower verbal production and reduced sentence complexity compared to healthy controls, while those with bipolar disorder...
PubMedで読む重要度 2
Machine learning reveals a multimodal, transdiagnostic signature of emotion dysregulation vulnerability across patients, offspring, and controls.
論文発表日: 2026-07-27
Molecular psychiatry
Medical Digest 収録日: 2026-07-29
This study used a transdiagnostic framework to identify early markers of emotion dysregulation (ED) in high-risk populations. A total of 237 participants completed a multimodal assessment. Principal component analysis (PCA) identified eight components, with two significantly differing between gro...
PubMedで読む皮膚科5 件
重要度 1
Spatial T lymphocyte infiltration into the primary melanoma tumor associates with survival.
論文発表日: 2026-07-28
Melanoma research
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Lipid-based nanocarriers as versatile platforms for curcumin delivery in photodynamic therapy of skin cancer.
論文発表日: 2026-07-27
International journal of pharmaceutics
Medical Digest 収録日: 2026-07-29
This study developed three curcumin lipid nanoparticles for non-melanoma skin cancer treatment. The nanoparticles showed improved skin penetration and enhanced cytotoxic and phototoxic effects compared to free curcumin. Specifically, A1Cur exhibited a hexagonal liquid-crystalline phase and demons...
PubMedで読む重要度 2
Reporting of Racial and Ethnic Diversity in Dermatology Clinical Trials Involving Canada, 2020 to 2025: A Systematic Review.
論文発表日: 2026-07-27
Journal of cutaneous medicine and surgery
Medical Digest 収録日: 2026-07-28
This study evaluated the reporting of race, ethnicity, and skin type in Canadian dermatology RCTs published between 2020 and 2025. Among 99 trials with 36,178 participants, race was reported in 93%, ethnicity in 39%, and Fitzpatrick skin type in 10%. Detailed racial or ethnic categories were pres...
PubMedで読む重要度 2
Oncolytic Virotherapy, Long Stalled, Nears Second Approval.
論文発表日: 2026-07-27
Cancer discovery
Medical Digest 収録日: 2026-07-28
この研究は、がん治療のための溶癌ウイルスの進展における課題を強調しており、T-VECが最初の承認され、RP1がメラノーマの次の候補であることが示されています。試験設計の欠陥、薬物組み合わせのタイミングの誤り、腫瘍の防御、そして送達の課題などの問題が進歩を妨げてきました。しかし、シーケンシングの進歩、新補助療法アプローチ、そして承認に近づいている膀胱がんウイルスは、この分野における新たな勢いを示唆しています。
PubMedで読む重要度 1
Palmoplantar pustulosis is associated with greater burden and impaired quality of life compared to psoriasis only: findings from a cross-sectional study within the Danish Skin Cohort.
論文発表日: 2026-07-27
Journal of the American Academy of Dermatology
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む眼科5 件
重要度 3
Innovations in glaucoma treatment: development and testing of a novel self-adjustable implant for effective pressure regulation.
論文発表日: 2026-07-27
Microsystems & nanoengineering
Medical Digest 収録日: 2026-07-29
This study introduces a compact, passive glaucoma implant designed to dynamically modulate hydraulic resistance and maintain intraocular pressure within physiological ranges. The implant effectively regulates pressure, mitigates early hypotony, and adapts to increasing downstream resistance. Ex v...
PubMedで読む重要度 2
Ocular Response Analyzer versus Goldmann Applanation Tonometry in a Population-based Sample: The Thessaloniki Eye Study.
論文発表日: 2026-07-27
American journal of ophthalmology
Medical Digest 収録日: 2026-07-29
This study compared corneal-compensated intraocular pressure (IOPcc) with Goldmann applanation tonometry (GAT-IOP) in an elderly cohort. Using data from the Thessaloniki Eye Study, it found that IOPcc was on average 2.75 mmHg higher than GAT-IOP. The prevalence of ocular hypertension increased fr...
PubMedで読む重要度 2
Real-World Outcomes of Faricimab for Polypoidal Choroidal Vasculopathy in a Multi-ethnic Cohort: A 12-Month Retrospective Study.
論文発表日: 2026-07-27
Ophthalmology and therapy
Medical Digest 収録日: 2026-07-29
この後ろ向きコホート研究は、多民族コホートにおける多発性脈絡膜血管腫症（PCV）に対するファリシマブ治療の12ヶ月間の転帰を評価しました。治療未経験の眼では、視力は+6.8文字（P < 0.01）改善し、CSTは-54 µm（P < 0.01）減少しました。治療経験のある眼では、視力の変化はわずか（+0.27文字、P > 0.05）でしたが、CSTは-40 µm（P < 0.01）減少しました。ファリシマブは、特に治療未経験の眼において臨床的に意味のある視力および解剖学的改善を示しました。これらの知見を検証するためには、適切な民族代表性を持つ前向き研究が必要です。
PubMedで読む重要度 2
Efficacy and safety at 12 months of PRESERFLO® combined with DuraGen® and morphological evaluation using AS-OCT.
論文発表日: 2026-07-27
Archivos de la Sociedad Espanola de Oftalmologia
Medical Digest 収録日: 2026-07-29
This prospective study evaluated the efficacy and safety of PRESERFLO® implantation combined with 0.04% MMC and DuraGen® in 50 eyes with moderate or severe glaucoma. The mean preoperative intraocular pressure (IOP) was 26.8 ± 7.1 mmHg, which decreased to 13.1 ± 4.5 mmHg, a reduction of 47.9% (p <...
PubMedで読む重要度 2
Association between Pre-diagnostic Macular Thickness With Risk of Age-related Macular Degeneration.
論文発表日: 2026-07-27
Retina (Philadelphia, Pa.)
Medical Digest 収録日: 2026-07-29
This study involving 40,078 participants from the UK Biobank aimed to determine if specific pre-diagnostic macular thickness patterns are linked to an increased risk of age-related macular degeneration (AMD). Using optical coherence tomography (OCT) imaging, two distinct macular thickness profile...
PubMedで読む小児科5 件
重要度 1
Artificial intelligence in pediatric medical genetics and genomics.
論文発表日: 2026-07-28
Current opinion in pediatrics
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
A Multitask Deep Learning Model for Pediatric Echocardiography Analysis.
論文発表日: 2026-07-28
Circulation
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Real-world effectiveness of maternal genetically inactivated acellular pertussis vaccination in protecting infants under three months of age: a case-control study using concurrent community-based and test-negative controls.
論文発表日: 2026-07-27
Infection
Medical Digest 収録日: 2026-07-29
This study evaluated the effectiveness of maternal aP vaccination in preventing pertussis in infants during an outbreak in Thailand. The case-control study included 33 symptomatic cases and 330 asymptomatic controls. Results showed that maternal vaccination significantly reduced the risk of pertu...
PubMedで読む重要度 2
Prevalence of Post-Intensive Care Syndrome in Paediatrics in children with CHD and association with health-related quality of life outcomes.
論文発表日: 2026-07-27
Cardiology in the young
Medical Digest 収録日: 2026-07-28
This study evaluated Post-intensive Care Syndrome in Paediatrics in CHD patients aged 5-18 years with at least one cardiac ICU admission. Using physical, cognitive, social, and emotional questionnaires, 80% of the 117 patients were found to have the syndrome, with 36% physical, 70% cognitive, 26%...
PubMedで読む重要度 2
Association between hyperchloremia and outcomes of children admitted to the pediatric intensive care unit (PICU) with diabetic ketoacidosis (DKA).
論文発表日: 2026-07-27
Journal of pediatric endocrinology & metabolism : JPEM
Medical Digest 収録日: 2026-07-28
This retrospective cohort study of 162 pediatric patients with diabetic ketoacidosis (DKA) found that hyperchloremia, present in 81.5% of patients, is associated with longer DKA resolution time, slower bicarbonate rise, and longer PICU stay. Hyperchloremia was predicted by lower body weight and t...
PubMedで読む救急医学5 件
重要度 1
Assessing readiness for large-scale combat operations across the full spectrum of medical and surgical capabilities.
論文発表日: 2026-08-01
The journal of trauma and acute care surgery
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Time Is Aorta: Can Artificial Intelligence Improve Surgical Timelines in Acute Type A Aortic Dissection? A Comprehensive Review.
論文発表日: 2026-08-01
Health science reports
Medical Digest 収録日: 2026-07-28
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Isolation Before Manipulation: A Stepwise Strategy for Emergency Multivisceral Resection of Colosplenic Fistula.
論文発表日: 2026-07-28
The American surgeon
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
The current evidence of 'peer-led' cardiopulmonary resuscitation training: a scoping review.
論文発表日: 2026-07-27
Clinical and experimental emergency medicine
Medical Digest 収録日: 2026-07-29
このスコーピングレビューは、様々な集団と環境におけるピア主導のCPRトレーニングに関する既存の証拠を探ることを目的としていました。合計37の研究が含まれ、4つのピアトレーニングモデルが特定されました。このレビューでは、ピア主導のトレーニングが専門家指導者主導のトレーニングと同様の教育成果を達成することがしばしばあることが分かりました。しかし、地域レベルでの実施と患者中心の成果に関する証拠は限られていました。より広範なコミュニティにおけるピア主導のCPRトレーニングの有効性と持続可能性を明確にするために、さらなる厳密な研究が必要です。
PubMedで読む重要度 2
Neglected traumatic hip dislocation: a systematic review of case reports and case series on management, outcomes, and complications.
論文発表日: 2026-07-27
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Medical Digest 収録日: 2026-07-29
This systematic review evaluated management strategies for neglected traumatic hip dislocation (NTHD), focusing on functional outcomes and complications. Twenty-one studies with 200 patients were analyzed. Open reduction is viable for dislocations less than 3 months, while THA is most reliable fo...
PubMedで読む外科5 件
重要度 1
[Effects of a structured language intervention based on predictive coding theory on patient experience and completion status of conventional gastroscopy].
論文発表日: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest 収録日: 2026-07-29
(Abstract too short for summarization)
PubMedで読む重要度 1
Development and Implementation of a Tiered Mentorship Program in a General Surgery Residency.
論文発表日: 2026-07-27
Journal of surgical education
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Renal paratransplant hernia: uncommon internal hernia with obscure and delayed presentation.
論文発表日: 2026-07-27
Polish archives of internal medicine
Medical Digest 収録日: 2026-07-29
（Abstract未提供）
PubMedで読む重要度 1
Cholecystectomy before diagnosis of primary sclerosing cholangitis is associated with markedly worsened transplant free survival.
論文発表日: 2026-07-27
JHEP reports : innovation in hepatology
Medical Digest 収録日: 2026-07-29
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 1
Model-based design and placement analysis for epidural cortical stimulation.
論文発表日: 2026-07-27
Journal of neural engineering
Medical Digest 収録日: 2026-07-28
（Abstract未提供）
PubMedで読む産婦人科5 件
重要度 3
The global impact of female infertility: regional disparities and future projections from the GBD 2021 study.
論文発表日: 2026-12-31
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Medical Digest 収録日: 2026-07-24
この研究は、1990年から2021年にかけて女性不妊症の世界的な増加が84.4%であり、1億1009万人に達したことを示しています。年齢標準化有病率も上昇しており、特に高いSDI地域では最も急速な成長が認められています。予測では、この傾向は2050年まで続くとされており、異なる経済的文脈における不妊症の特定の要因に対処するための戦略を検討する必要があります。
PubMedで読む重要度 3
Placental 3D Doppler and uterine artery Doppler for predicting adverse outcomes in placenta accreta: a retrospective cohort study.
論文発表日: 2026-12-01
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Medical Digest 収録日: 2026-07-25
この研究は、胎盤接着スペクトラム（PAS）を有する患者さんにおける超音波測定の予測値が妊娠における有害事象（APOs）に与える影響を調査しました。180人のPASを有する女性のうち、42.22%が合併症を経験しました。研究では、合併症のある患者さんは、胎盤血流が高く、子宮動脈抵抗が低いことが示されました。6つの超音波パラメータの組み合わせモデルはリスク層別化を改善し、高リスクの女性の84%を正確に特定し、低リスクの女性の62%を除外しました。このモデルは、PASに影響を受けた妊娠の監視と管理において臨床医を支援し、重篤な合併症のリスクを低下させる可能性があります。
PubMedで読む重要度 2
Oocyte maturation and pregnancy outcomes in relation to gonadotropin duration in antagonist cycles.
論文発表日: 2026-12-01
Annals of medicine
Medical Digest 収録日: 2026-07-26
This retrospective study of 9372 GnRH antagonist cycles found that gonadotropin stimulation duration is associated with oocyte maturation and pregnancy outcomes, even after adjusting for confounders. The optimal duration for achieving the highest likelihood of clinical pregnancy and live birth is...
PubMedで読む重要度 1
Re-evaluating low-molecular-weight heparin use in recurrent missed miscarriage: current evidence and future directions.
論文発表日: 2026-12-01
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Medical Digest 収録日: 2026-07-26
(Summary generation failed. Please refer to the original article.)
PubMedで読む重要度 2
Managing TRAP Sequence Conservatively: A Case Report of Full-Term Pregnancy With Favorable Outcome.
論文発表日: 2026-08-01
Clinical case reports
Medical Digest 収録日: 2026-07-25
アカーディックツイン、またはTRAPシーケンスは、異常な胎盤血流による片方の双子の重度の奇形を特徴とする単絨毛膜双胎の稀な状態です。30歳の女性の症例研究では、第二トリメスターにおいて無頭のアカーディックツインが診断されました。アカーディックツインの予後は不良であり、死亡率は100%であり、ポンプツインの死亡率は50%-55%です。妊娠は保守的に管理され、38週まで継続され、選択的帝王切開に至りました。これは、ポンプツインに合併症の兆候がない場合の保守的管理の重要性を強調しています。
PubMedで読む