Name: Medical Digest
Author: Medical Digest

피부과5 편

영향력 2

Efficacy and drug survival after transitioning to IL-17 inhibitors in patients with psoriasis who did not respond to IL-23 inhibitors: analysis from the BIOREP registry.

발표일: 2026-12-01

The Journal of dermatological treatment

Medical Digest 수록일: 2026-07-11

This study analyzed the efficacy of switching from IL-23 inhibitors to IL-17 inhibitors in psoriasis patients. Out of 102 patients, 90.2% switched due to insufficient efficacy of IL-23 inhibitors. After 3 months, 82.6% achieved PASI-75, and 66.3% reached an absolute PASI ≤ 1. The overall survival...

PubMed에서 읽기

영향력 2

Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization.

발표일: 2026-09-01

International journal of molecular medicine

Medical Digest 수록일: 2026-07-11

This study highlights the role of metabolic dysregulation, particularly phenylalanine accumulation, in psoriasis pathogenesis. It demonstrates that a high-phenylalanine diet worsens skin inflammation, while dietary restriction or L-type amino acid transporter inhibitors can alleviate it. The find...

PubMed에서 읽기

영향력 3

Prognostic Factors in Primary Head and Neck Cutaneous Squamous Cell Carcinoma: A Large-Scale, Multi-Institutional Competing-Risks Analysis.

발표일: 2026-07-12

Journal of surgical oncology

Medical Digest 수록일: 2026-07-14

This study analyzed data from 8,610 patients with head and neck cutaneous squamous cell carcinoma to identify independent prognostic factors. Key findings include that tumor diameter, poor differentiation, deep invasion, and large-caliber perineural invasion are critical predictors of outcomes. A...

PubMed에서 읽기

영향력 2

Cross-Sectional Survey of Unmet Needs in Children With NF1 and Cutaneous Neurofibromas: The Role of Pediatric Dermatology.

발표일: 2026-07-12

Pediatric dermatology

Medical Digest 수록일: 2026-07-14

This study assessed pediatric dermatologists' roles and barriers in treating neurofibromatosis type 1 (NF1) through a survey of 131 respondents. It found that while these specialists are engaged in diagnosis and follow-up, they are underrepresented in multidisciplinary clinics, with surgical exci...

PubMed에서 읽기

영향력 2

Selective Depletion of Tumor-Infiltrating CD4

발표일: 2026-07-12

Cancer science

Medical Digest 수록일: 2026-07-14

This study highlights the role of regulatory T cells in ovarian cancer and the challenges in developing strategies to target these cells effectively.

PubMed에서 읽기

의학 연구 트렌드

피부과5 편

Efficacy and drug survival after transitioning to IL-17 inhibitors in patients with psoriasis who did not respond to IL-23 inhibitors: analysis from the BIOREP registry.

Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization.

Prognostic Factors in Primary Head and Neck Cutaneous Squamous Cell Carcinoma: A Large-Scale, Multi-Institutional Competing-Risks Analysis.

Cross-Sectional Survey of Unmet Needs in Children With NF1 and Cutaneous Neurofibromas: The Role of Pediatric Dermatology.

Selective Depletion of Tumor-Infiltrating CD4

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