CCaS: A New Conceptual Framework in Cerebrovascular Disease.
Published: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedThis week's highest-impact publications across 29 specialties, curated by AI
Last updated: 28 de jul. de 2026
Published: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
The abstract emphasizes the importance of mentorship and knowledge transfer in stroke medicine, highlighting how mentors pass down their knowledge and experience to mentees. It underscores the significance of cultivating the next generation of leaders in this field, suggesting that this process i...
Read on PubMedPublished: 2026-07-28
Blood advances
Medical Digest Indexed: 2026-07-29
The phase 2 ACE-WM-001 trial assessed acalabrutinib in 106 patients with Waldenström macroglobulinemia, showing overall response rates of 92.9% and 94.6% for treatment-naive and relapsed/refractory cohorts, respectively. Median progression-free survival was not estimable for treatment-naive and 6...
Read on PubMedPublished: 2026-07-28
Kardiologia polska
Medical Digest Indexed: 2026-07-29
This study analyzed 749,235 coronary angiographies from Poland's National Registry of Procedures of Invasive Cardiology database, focusing on trends in non-obstructive coronary artery disease. Findings showed an increase in non-obstructive lesions and a decrease in normal angiograms. Higher body ...
Read on PubMedPublished: 2026-07-28
Blood advances
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Cancer letters
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Cell reports
Medical Digest Indexed: 2026-07-29
This study identifies GBP6 as a mitochondrial factor associated with aggressive cervical cancer, enriched in high-risk tumors and correlating with poor clinical outcomes. GBP6 knockdown suppresses tumor cell proliferation and promotes cell death by disrupting mitochondrial bioenergetics and induc...
Read on PubMedPublished: 2026-07-27
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Medical Digest Indexed: 2026-07-29
This study focuses on reprogramming myofibroblastic cancer-associated fibroblasts (CAFs) into immune activated antigen presenting CAFs (apCAFs) as a treatment for fibrotic breast cancer. Using a spatiotemporally ultrasound-controlled nanoparticle, the researchers successfully reprogrammed myCAFs ...
Read on PubMedPublished: 2026-07-27
Journal for immunotherapy of cancer
Medical Digest Indexed: 2026-07-29
This study explores the role of mitophagy in cancer immunogenicity, identifying TOMM40 as a gatekeeper of mitochondrial import that restrains mitophagy. Loss of TOMM40 induces mitochondrial dysfunction and hyperactivated mitophagy, converting immune-cold tumors into immune-inflamed states with in...
Read on PubMedPublished: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
Annals of clinical and translational neurology
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Neuropsychologia
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Medical Digest Indexed: 2026-07-29
This study identifies the immunoproteasome subunit LMP2 as a key regulator of astrocyte reactivity and neuroinflammatory outcomes following ischemic stroke. Using knockout models, researchers found that LMP2 deficiency reduces infarct volume, attenuates neuroinflammation, and improves neurologica...
Read on PubMedPublished: 2026-07-28
Cancer letters
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Journal of gastrointestinal cancer
Medical Digest Indexed: 2026-07-29
This study found that protein-energy malnutrition (PEM) affects one in five hospitalizations among young adults with gastrointestinal cancers. PEM was associated with higher in-hospital mortality, longer hospital stays, and increased hospital charges. Adjusted analyses showed PEM was independentl...
Read on PubMedPublished: 2026-07-27
Pediatric surgery international
Medical Digest Indexed: 2026-07-29
This study evaluated the use of machine learning models to predict 2-year native liver survival (NLS) in biliary atresia (BA) patients following Kasai portoenterostomy (KPE). Data from 154 BA patients were analyzed using traditional machine learning algorithms, with the random forest model showin...
Read on PubMedPublished: 2026-07-27
Journal of robotic surgery
Medical Digest Indexed: 2026-07-28
This bibliometric analysis of 126 papers on robotic cholecystectomy for gallstone disease reveals a growing trend in research output, particularly after 2021. The United States leads in research productivity, with a significant shift in focus from conventional laparoscopic management to robotic s...
Read on PubMedPublished: 2026-07-27
Biomedical physics & engineering express
Medical Digest Indexed: 2026-07-28
This study introduces BMSNet, a boundary-guided multi-scale network for accurate polyp segmentation in colonoscopy images. The method uses a Scale-Aware Modulation Meets Transformer-T backbone and includes a boundary prediction module and a boundary-guided feature enhancement module. BMSNet achie...
Read on PubMedPublished: 2026-12-01
Journal of enzyme inhibition and medicinal chemistry
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Cancer letters
Medical Digest Indexed: 2026-07-29
This study highlights the role of neutrophil extracellular traps (NETs) in lung cancer progression, particularly in high-stiffness tumor niches. Using AFM and mIF, the researchers demonstrated a spatial correlation between NETs formation and ECM stiffness, suggesting that targeting NETs could imp...
Read on PubMedPublished: 2026-07-28
The Pediatric infectious disease journal
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
The Pediatric infectious disease journal
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
The Pediatric infectious disease journal
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest Indexed: 2026-07-29
(Abstract too short for summarization)
Read on PubMedPublished: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest Indexed: 2026-07-29
(Abstract too short for summarization)
Read on PubMedPublished: 2026-07-28
British journal of clinical pharmacology
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Circulation
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-27
European journal of pediatrics
Medical Digest Indexed: 2026-07-29
This study found that normal-weight adolescents with polycystic ovary syndrome (PCOS) have greater visceral adiposity compared to healthy controls, even after adjusting for BMI percentile. Triglycerides and the TG/HDL-C ratio were higher in the PCOS group but should be interpreted cautiously in r...
Read on PubMedPublished: 2026-07-28
Journal of nephrology
Medical Digest Indexed: 2026-07-29
This study assessed the care of dialysis-requiring acute kidney injury (AKI-D) across Italy, revealing that AKI-D accounts for 20% to over 60% of dialysis-unit activity. Kidney replacement therapy is often provided outside nephrology wards, primarily in cardiac ICUs and emergency departments. Con...
Read on PubMedPublished: 2026-07-28
Journal of ultrasound
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Journal of robotic surgery
Medical Digest Indexed: 2026-07-28
This umbrella review compared robot-assisted kidney transplantation (RAKT) and open kidney transplantation (OKT) using systematic reviews and meta-analyses. RAKT showed better perioperative outcomes such as reduced blood loss and surgical site infections but open surgery had advantages in certain...
Read on PubMedPublished: 2026-07-27
Scientific reports
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Journal of clinical anesthesia
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-12-31
Autoimmunity
Medical Digest Indexed: 2026-07-27
This study involving 235 patients with systemic lupus erythematosus (SLE) found that lower serum interleukin-2 (IL-2) levels were associated with specific hematological abnormalities, including anemia, leukopenia, and lymphopenia. Using multivariate regression analysis, the study identified signi...
Read on PubMedPublished: 2026-12-31
Gut microbes
Medical Digest Indexed: 2026-07-24
This study highlights the role of gut microbiota dysbiosis and host protein glycosylation in the immune signaling involved in the progression of rheumatoid arthritis (RA).
Read on PubMedPublished: 2026-08-01
Health science reports
Medical Digest Indexed: 2026-07-28
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
The Analyst
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-25
Phytomedicine : international journal of phytotherapy and phytopharmacology
Medical Digest Indexed: 2026-07-26
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-12-01
Virulence
Medical Digest Indexed: 2026-07-29
This review discusses the formation process of biofilms, mechanisms of antibiotic tolerance and resistance, and new intervention approaches. Biofilms, with their stable structure and protective mechanisms, pose a significant challenge in eradicating clinical infections. The review highlights the ...
Read on PubMedPublished: 2026-07-28
Zhonghua wai ke za zhi [Chinese journal of surgery]
Medical Digest Indexed: 2026-07-29
(Abstract too short for summarization)
Read on PubMedPublished: 2026-07-27
The Lancet. Infectious diseases
Medical Digest Indexed: 2026-07-29
In sub-Saharan Africa, advanced HIV patients hospitalized with high mortality rates often have undiagnosed tuberculosis. Despite concerns about toxicity and drug interactions, short-term empiric antituberculous therapy appears safe and may improve survival in high-risk patients. A paradigm shift ...
Read on PubMedPublished: 2026-07-27
Current microbiology
Medical Digest Indexed: 2026-07-29
This study analyzed 144 E. coli strains to investigate the correlation between phylogenetic groups and antibiotic resistance. Clinical isolates showed high resistance to cephalosporins and fluoroquinolones, while food-derived strains had lower resistance levels. Phylogroup A had the highest preva...
Read on PubMedPublished: 2026-07-27
Current microbiology
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-08-01
EJHaem
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-08-01
Stroke
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
The Pediatric infectious disease journal
Medical Digest Indexed: 2026-07-29
This study highlights the extensive and heterogeneous use of antifungal agents in pediatric oncology and hematopoietic stem cell transplantation settings, with a heavy reliance on prophylactic and empiric strategies and minimal targeted therapy. The findings underscore the need for structured ant...
Read on PubMedPublished: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest Indexed: 2026-07-29
The incidence of mucormycosis is increasing among patients with hematologic malignancies and those undergoing hematopoietic stem cell transplantation in China. A consensus led by the Mycology Committee of the Chinese Medical Education Association, involving 23 experts, was developed to address th...
Read on PubMedPublished: 2026-07-28
Blood advances
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-28
Proceedings of the National Academy of Sciences of the United States of America
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Psychological medicine
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Proceedings of the National Academy of Sciences of the United States of America
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Cognitive neuropsychiatry
Medical Digest Indexed: 2026-07-29
This study evaluated cognitive functioning and linguistic measures in patients with schizophrenia, bipolar disorder, and healthy controls. Participants with schizophrenia showed lower verbal production and reduced sentence complexity compared to healthy controls, while those with bipolar disorder...
Read on PubMedPublished: 2026-07-27
Molecular psychiatry
Medical Digest Indexed: 2026-07-29
This study used a transdiagnostic framework to identify early markers of emotion dysregulation (ED) in high-risk populations. A total of 237 participants completed a multimodal assessment. Principal component analysis (PCA) identified eight components, with two significantly differing between gro...
Read on PubMedPublished: 2026-07-28
Melanoma research
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
International journal of pharmaceutics
Medical Digest Indexed: 2026-07-29
This study developed three curcumin lipid nanoparticles for non-melanoma skin cancer treatment. The nanoparticles showed improved skin penetration and enhanced cytotoxic and phototoxic effects compared to free curcumin. Specifically, A1Cur exhibited a hexagonal liquid-crystalline phase and demons...
Read on PubMedPublished: 2026-07-27
Journal of cutaneous medicine and surgery
Medical Digest Indexed: 2026-07-28
This study evaluated the reporting of race, ethnicity, and skin type in Canadian dermatology RCTs published between 2020 and 2025. Among 99 trials with 36,178 participants, race was reported in 93%, ethnicity in 39%, and Fitzpatrick skin type in 10%. Detailed racial or ethnic categories were pres...
Read on PubMedPublished: 2026-07-27
Cancer discovery
Medical Digest Indexed: 2026-07-28
This study highlights the challenges in advancing oncolytic viruses for cancer treatment, with T-VEC being the first approved and RP1 as the next candidate for melanoma. Issues such as flawed trial designs, mistimed drug combinations, tumor defenses, and delivery challenges have hindered progress...
Read on PubMedPublished: 2026-07-27
Journal of the American Academy of Dermatology
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-27
Microsystems & nanoengineering
Medical Digest Indexed: 2026-07-29
This study introduces a compact, passive glaucoma implant designed to dynamically modulate hydraulic resistance and maintain intraocular pressure within physiological ranges. The implant effectively regulates pressure, mitigates early hypotony, and adapts to increasing downstream resistance. Ex v...
Read on PubMedPublished: 2026-07-27
American journal of ophthalmology
Medical Digest Indexed: 2026-07-29
This study compared corneal-compensated intraocular pressure (IOPcc) with Goldmann applanation tonometry (GAT-IOP) in an elderly cohort. Using data from the Thessaloniki Eye Study, it found that IOPcc was on average 2.75 mmHg higher than GAT-IOP. The prevalence of ocular hypertension increased fr...
Read on PubMedPublished: 2026-07-27
Ophthalmology and therapy
Medical Digest Indexed: 2026-07-29
This retrospective cohort study evaluated the 12-month outcomes of faricimab treatment for polypoidal choroidal vasculopathy (PCV) in a multi-ethnic cohort. In treatment-naïve eyes, visual acuity improved by +6.8 letters (P < 0.01) and CST reduced by -54 µm (P < 0.01). In treatment-experienced ey...
Read on PubMedPublished: 2026-07-27
Archivos de la Sociedad Espanola de Oftalmologia
Medical Digest Indexed: 2026-07-29
This prospective study evaluated the efficacy and safety of PRESERFLO® implantation combined with 0.04% MMC and DuraGen® in 50 eyes with moderate or severe glaucoma. The mean preoperative intraocular pressure (IOP) was 26.8 ± 7.1 mmHg, which decreased to 13.1 ± 4.5 mmHg, a reduction of 47.9% (p <...
Read on PubMedPublished: 2026-07-27
Retina (Philadelphia, Pa.)
Medical Digest Indexed: 2026-07-29
This study involving 40,078 participants from the UK Biobank aimed to determine if specific pre-diagnostic macular thickness patterns are linked to an increased risk of age-related macular degeneration (AMD). Using optical coherence tomography (OCT) imaging, two distinct macular thickness profile...
Read on PubMedPublished: 2026-07-28
Current opinion in pediatrics
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
Circulation
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Infection
Medical Digest Indexed: 2026-07-29
This study evaluated the effectiveness of maternal aP vaccination in preventing pertussis in infants during an outbreak in Thailand. The case-control study included 33 symptomatic cases and 330 asymptomatic controls. Results showed that maternal vaccination significantly reduced the risk of pertu...
Read on PubMedPublished: 2026-07-27
Cardiology in the young
Medical Digest Indexed: 2026-07-28
This study evaluated Post-intensive Care Syndrome in Paediatrics in CHD patients aged 5-18 years with at least one cardiac ICU admission. Using physical, cognitive, social, and emotional questionnaires, 80% of the 117 patients were found to have the syndrome, with 36% physical, 70% cognitive, 26%...
Read on PubMedPublished: 2026-07-27
Journal of pediatric endocrinology & metabolism : JPEM
Medical Digest Indexed: 2026-07-28
This retrospective cohort study of 162 pediatric patients with diabetic ketoacidosis (DKA) found that hyperchloremia, present in 81.5% of patients, is associated with longer DKA resolution time, slower bicarbonate rise, and longer PICU stay. Hyperchloremia was predicted by lower body weight and t...
Read on PubMedPublished: 2026-08-01
The journal of trauma and acute care surgery
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-08-01
Health science reports
Medical Digest Indexed: 2026-07-28
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-28
The American surgeon
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Clinical and experimental emergency medicine
Medical Digest Indexed: 2026-07-29
This scoping review aimed to explore existing evidence on peer-led CPR training across various populations and settings. A total of 37 studies were included, identifying four peer-training models. The review found that peer-led training often achieved similar educational outcomes to professional ...
Read on PubMedPublished: 2026-07-27
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Medical Digest Indexed: 2026-07-29
This systematic review evaluated management strategies for neglected traumatic hip dislocation (NTHD), focusing on functional outcomes and complications. Twenty-one studies with 200 patients were analyzed. Open reduction is viable for dislocations less than 3 months, while THA is most reliable fo...
Read on PubMedPublished: 2026-07-28
Zhonghua yi xue za zhi
Medical Digest Indexed: 2026-07-29
(Abstract too short for summarization)
Read on PubMedPublished: 2026-07-27
Journal of surgical education
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Polish archives of internal medicine
Medical Digest Indexed: 2026-07-29
(No abstract provided)
Read on PubMedPublished: 2026-07-27
JHEP reports : innovation in hepatology
Medical Digest Indexed: 2026-07-29
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-07-27
Journal of neural engineering
Medical Digest Indexed: 2026-07-28
(No abstract provided)
Read on PubMedPublished: 2026-12-31
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Medical Digest Indexed: 2026-07-24
This study highlights the significant rise in female infertility globally, with cases increasing by 84.4% from 1990 to 2021, reaching 110.09 million. The age-standardized prevalence rate is also on the rise, particularly in high SDI regions, which show the fastest growth. Projections indicate tha...
Read on PubMedPublished: 2026-12-01
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Medical Digest Indexed: 2026-07-25
This study investigates the predictive value of ultrasound measures in patients with placenta accreta spectrum (PAS) for adverse pregnancy outcomes (APOs). Among 180 women with PAS, 42.22% experienced complications. The study found that those with complications exhibited higher placental blood fl...
Read on PubMedPublished: 2026-12-01
Annals of medicine
Medical Digest Indexed: 2026-07-26
This retrospective study of 9372 GnRH antagonist cycles found that gonadotropin stimulation duration is associated with oocyte maturation and pregnancy outcomes, even after adjusting for confounders. The optimal duration for achieving the highest likelihood of clinical pregnancy and live birth is...
Read on PubMedPublished: 2026-12-01
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Medical Digest Indexed: 2026-07-26
(Summary generation failed. Please refer to the original article.)
Read on PubMedPublished: 2026-08-01
Clinical case reports
Medical Digest Indexed: 2026-07-25
Acardiac twinning, or TRAP sequence, is a rare condition in monochorionic twins characterized by severe malformation of one twin due to abnormal placental blood flow. In a case study of a 30-year-old woman, an acephalus acardiac twin was diagnosed during the second trimester. The prognosis for th...
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